科研进展脂肪抑制T2WI和ASL融合

CanFS-T2/ASLfusionimagebeanalternativetoT1enhancedimaginginNasopharyngealcarcinoma?

MengLin1,XiaoduoYu1,HanOuyang1,DehongLuo1,ChunwuZhou1,andBingWu2

1CancerHospital,ChineseAcademyofMedicalSciences,Beijing,China,PeoplesRepublicof,2GEHealthcareMRresearchChina,Beijing,Beijing,China,PeoplesRepublicof

TumorextentassessmentofNPCiscriticalfordelineatingtheradio-therapeutictargetregion.Weaimedtoinvestigatetheuseofthefusionimagesoffatsuppressed(FS)-T2witharterialspinlabeling(ASL)inmeasuringthevolumeofNPC.Twoobserversmeasuredthevolumeof21untreatedNPCusingFS-T2,FS-T2/ASL(withPLD=1.0,1.5and2.0s)fusionimagesandenhanced-T1WIseparately.ComparedtothoseobtainedusingFS-T2alone,measurementsmadeusingFS-T2/ASLweremoreconsistentwiththosemadeusingenhanced-T1WI.TheFS-T2/ASLfusionimagehasthepotentialtobeanalternativetoenhanced-T1WI,whencontrastadministrationcannotbeperformed.

Nasopharyngealcarcinoma(NPC)isatypeofmalignantheadandnecktumor.Imagingisneededtoassesstheextentofthetumorforstaginganddelineatingthetargetregionofradiotherapy.InMRI,contrastenhancedT1hasadvantagesinNPCdiagnosisandstagingduetotheimprovedcontrastnoiseratiobetweentumorandsurroundingtissue(suchasfatandmuscle)1,itisalsotheonlyMRexaminationre